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Thursday, December 13, 2012

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baby04 Infant DNA Tests Speed Diagnosis of Rare Diseases

Benefits of DNA Testing
The most accurate way for physicians to diagnose genetic disorders in newborn infants is DNA testing, which is the thorough examination of the DNA molecule. Children’s Mercy Hospital of Kansas City, MO, is using a new test that provides results in a couple of days versus the typical weeks or even months in the past. The test is designed to specifically identify disease causing mutations.
This new DNA examination is not in widespread use at this time as research is ongoing. The facts are one in 20 newborns in neonatal intensive care units have a genetic disease. Faulty genes have been found in 3,500 of the 7,500 known genetic diseases.
Since the completion of the Human Genome Project Analysis a large amount of data analysis will be ongoing for many years. In this project approximately 20,000 to 25,000 genes were identified, along with the sequencing of the 3 billion chemical base pairs that make up human DNA.
There are numerous accredited laboratories where it is possible to get accurate DNA testing for paternity testing. When looking for a laboratory to have DNA testing, it is important to seek out one that has several accreditations from governing agencies.
Some of the accrediting agencies to seek out are:
  • American Association of Blood Banks, which requires a rigorous review with an inspection of the testing processes and the laboratory.
  • National Association of Testing Authorities (NATA), which is the most difficult accreditation to obtain due to its difficult quality and security requirements.
  • Safe Harbor requires data protection, providing privacy protection for the European Union.
  • ISO 17025 accreditation assures technical competence with the calibrations and testing labs.
  • A2LA accreditation system is the largest multi-discipline system in the United States, which is recognized by Accreditation Bodies in the European Union and other international countries.
DNA tests only require a buccal swab, which is painless swab from inside of the cheek from an infant or adult. The testing may also be completed with a blood
sample from a finger prick. DNA sampling for a paternity test, particularly if it is legally binding, requires a swab from the mother, child and alleged father. This is the most accurate way to determine paternity and a good laboratory will require 16 identity markers for accuracy. One of those markers determines the sex of the person. Accuracy can reach 99.99999 percent.
There are many types of tests that may be ordered from the laboratory. For instance, a DNA Predisposition Test reveals the predisposition for 25 different diseases and conditions. DNA testing can be completed to look for ancestral origins. An Infidelity DNA Test can test a wide range of garments or objects for DNA. There is a Zygosity DNA Twin that will confirm whether twins are fraternal or identical. Furthermore, there are tests for grandparents, aunts and uncles. Prenatal paternity testing may also be completed before birth. There is also an Immigration DNA Test and a Missing Parent Test that may help law enforcement.
Finally, two people may get a DNA test to see if they are related. DNA testing may be done through the mail and is confidential, with the results being mailed in a plain envelope. Accuracy is guaranteed with an accredited laboratory and DNA testing if very affordable.

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1 comment:

  1. I want to thank you for this informative post. I really appreciate sharing this great post. Keep up your work. Thanks for sharing this great article. Great information thanks a lot for the detailed article.
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